Clinical Trials in Degenerative Diseases

RESEARCH ARTICLE
Year
: 2019  |  Volume : 4  |  Issue : 3  |  Page : 70--75

Effects of electroanalgesia on knee osteoarthritis: study protocol for a randomized, triple-blind, placebo-controlled trial


Camila Cadena Almeida, Klaus Porto Azevedo, Tatiana Andrade Cacho, Júlia B. L. Garcia Leal, Geovanna Nascimento Montanini, Danielly Nery T. Silva, Patrícia Azevedo Garcia, João Luiz Quagliotti Durigan 
 Muscle Tendon Plasticity Research Group from University of Brasilia, Brasília, Brazil

Correspondence Address:
Camila Cadena Almeida
Muscle Tendon Plasticity Research Group from University of Brasilia, Brasília
Brazil

Background and objectives: Osteoarthritis of the knee is considered the major cause of pain and dysfunction of the motor apparatus and mainly affects female individuals over 60 years. Electrotherapy presents a reasonable level of evidence for pain control and inconsistent results. Thus, this study aims to verify the efficacy of electroanalgesia, using different currents, for knee osteoarthritis. Subjects and methods: This is a randomized, triple-blind, placebo-controlled clinical trial. Individuals will be randomly divided into four groups, and subjected to four different types of currents: transcutaneous electric nerve stimulation in Group 1, bipolar interferential current in Group 2, Aussie in Group 3, and placebo in Group 4, presenting different modulations and 20 minutes of intervention each. Patients have been recruited since August 2017. The primary outcome measures will be analyzed in June 2020 and the study will finish in August 2020. Protocol version: 1.0. This study was approved by the Ethics Committee of University of Brasilia on July 18, 2017 (CAEE: 62256516.2.0000.0030). Outcome measures: Primary and secondary outcomes will be analyzed at baseline, 1, 3 and 6 months after the start of the study. The primary outcome is pain assessed by numerical verbal scale, pain-pressure threshold, and brief pain inventory. The secondary outcomes are function and quality of life (including Western Ontario and McMaster Universities Osteoarthritis Index, The Medical Outcomes Study 36-item Short-Form Health Survey, Timed Get-Up-and-Go test, 30-second Sit-to-Stand test, Stair-ascend test, 6-minute walk test, 40-meter fast-walk test). Discussion: We hope to provide evidence for finding suitable electroanalgesia on knee osteoarthritis. Trial registration: Registered in the Brazilian Clinical Trials Registry (ReBEC) (RBR-875zsw) on November 24, 2017.


How to cite this article:
Almeida CC, Azevedo KP, Cacho TA, Leal JB, Montanini GN, Silva DN, Garcia PA, Durigan JL. Effects of electroanalgesia on knee osteoarthritis: study protocol for a randomized, triple-blind, placebo-controlled trial.Clin Trials Degener Dis 2019;4:70-75


How to cite this URL:
Almeida CC, Azevedo KP, Cacho TA, Leal JB, Montanini GN, Silva DN, Garcia PA, Durigan JL. Effects of electroanalgesia on knee osteoarthritis: study protocol for a randomized, triple-blind, placebo-controlled trial. Clin Trials Degener Dis [serial online] 2019 [cited 2019 Dec 16 ];4:70-75
Available from: http://www.clinicaltdd.com/article.asp?issn=2542-3975;year=2019;volume=4;issue=3;spage=70;epage=75;aulast=Almeida;type=0